Vous êtes ici

Composition de l'équipe et publis au 31 Mai 2017

Publications_equipe_UMRS1122_IGEPCV_BMS.220617.pdf

COMPOSITION DE L’UMR INSERM U1122; IGE-PCV (Organigramme fonctionnel)

01 Janvier 2017

 

PERSONNEL CHERCHEUR PERMANENT

Chercheur INSERM

  • SIEST Sofia*, DR1 – HDR (100 %), Directeur

Hospitalo-Universitaires

  • KLEIN Marc, PUPH – HDR (33 %)
  • WERYHA Georges, PUPH – HDR (33 %)

Enseignants-chercheurs MENESR

  • DADE Sébastien, MCF (50 %)

 

PERSONNEL ITA-BIATSS

INSERM

  • STATHOPOULOU Maria*, Ingénieur de Recherche - ACT (100%)

MENESR

  • HIEGEL Brigitte*, Adjoint Technique (100%)
  • MASSON Christine*, Technicienne (100 %)

 

PERSONNEL ASSOCIE

Enseignants-chercheurs

  • ZIAD ALIZADEH Behrooz, MD, PR – HDR (25 %) - Université de Groningen, Pays-bas
  • EL SHAMIEH Said, MCF (25 %) - Université Libanaise, Beyrouth, Liban
  • RANCIER Marc, Clinicien, MD, PhD (50 %) - Hôpitaux Robert Schuman, Luxembourg

 

PERSONNEL NON PERMANENT

Secrétariat

  • ULMER Patricia, Technicienne (jusqu’au 1er Juin 2016 – 100 % ITA INSERM, depuis vacataire INSERM – 25%)

Post-Doctorant

  • SALEH Abdelsalam (100 %)
  • AKBAR Samina (100 %)

Ingénieur d’Etudes (en cours de recrutement)

  • PETRELIS Alexandros (100 %)

Thésards Université de Lorraine

1ère année

  • NADERI Elnaz (100 % - thèse en co-tutelle avec Université de Gröningen)
  • GORNEJAK Vesna (100 %)

3ème année

  • ALDASORO ARGUINANO Alex-Ander (100 %)
  • XIE Ting (100 %)
  • CHATELIN Jérôme (50 %)

Master 2

  • MOOG Sophie (100 %)

ETP : 15,41

* personnel impliqué au CRB IGE-PCV

 

PERSONNEL EN APPUI

Avec % non quantifiable

Aide logistique pour la partie administrative et financière

 

1. Plateforme secrétariat INSERM, Strasbourg:

  • PARENTIN Elisabeth (TCS)
  • CATALDI Isabelle (TCS)
  • MURIC Elmana (TCN)
  • EHRHARDT Marie Françoise (TCN)

2. Plateforme d'organisation de congrès « Com&Co », Marseille:    

  • RICHIER Benjamin
  • JARRY Etienne          

Soutien Informatique

U LORRAINE:

  • DUGRAVOT Christophe
  • REMY-ARECOL François

INSERM:

  • KULAHCI Mustapha

Aide de Recherche sur VEGF

VEGF Consortium (Coordinateur: SIEST Sofia):

  • Queen Mary University of London (QMU) – DELOUKAS Panos
  • Boston University (BU) –  SESHADRI Sudha
  • Randox Laboratories Limited  – LAMONT John
  • Univerza V Ljubljani (UL) – MARC Janja
  • Fondazione Luigi Maria Monti( IDI-IRCCS), Universita di Roma (UniRoma1) – SIMMACO Maurizio
  • European Society of Pharmacogenomics and Personalised Therapy (ESPT) – VAN SCHAIK Ron
  • Biobanking and Biomolecular Resources Research Infrastructure (BBMRI) / INSERM US 13, BIOBANQUES – DAGHER Georges
  • University Medical Center of Groningen (UMCG) – ZIAD ALIZADEH Behrooz
  • Institute of genetics and biophysics, National Research Council of Italy (IGB-CNR) – CIULLO Marina       
  • University College London (UCL) – CASAS Juan P.
  • Luxembourg Centre for Systems Biomedicine, University of Luxembourg (ULUX)  – SCHNEIDER Jochen
  • Institut de Cancérologie de Lorraine (ICL), CNRS UMR7039 CRAN (UL) – MERLIN Jean Louis
  • University of North Carolina ( UNC) – INNOCENTI Federico

Aide à la valorisation des résultats

Industrie du diagnostique: Randox Laboratories Limited, Belfast 

  • FITZGERALD Peter
  • LAMONT John
  • MURRAY Helena
  • KURTH Mary Joe

Aide à la communication / Formation / Education

Plateforme ESPT (Président, SIEST Gérard† (le 9 Avril 2016), depuis VAN SCHAIK Ron; Trésorier et Président de la division Congres et réunions, SIEST Sofia):

* Division of Education and Course:      

  • MANOLOPOULOS Vangelis G.
  • MARC Janja       

* Division of Scientific and Clinical Implementation:

  • VAN SCHAIK Ron    
  • ANSARI Marc     
  • LLERENA Adrian 

* Division of Communication and External Relations:

  • SIMMACO Maurizio  
  • CASCORBI Ingolf    
  • LLERENA Adrian  

 

Liste des publications de la structure 2011-2017

  1. Publications Internationales (ACLIN) au sein de l’unité
  1. PUBLICATIONS ORIGINALES DANS DES REVUES A COMITE DE LECTURE
  2. PUBLICATIONS DE REVUES DANS DES JOURNAUX DE SPECIALITE A COMITE DE LECTURE
  3. PUBLICATIONS EFFECTUEES DANS LE CADRE DE CONGRES INTERNATIONAUX / ABSTRACTS DANS DES JOURNAUX A COMITE DE LECTURE
  4. PUBLICATIONS DIDACTIQUES - RECOMMENDATIONS
  1. Publications Nationales (ACLN) au sein de l’unité
  2. Conférences invitées (INV) au sein de l’unité
  3. Publications hors unité (PHU)

 

P (premier Auteur); D (dernier Auteur); C  (en collaboration) ; CL (clinique) ; CO (cohorte)

 

______________________

 

  1. Publications Internationales (ACLIN) au sein de l’unité

 

     1/ PUBLICATIONS ORIGINALES DANS DES REVUES A COMITE DE LECTURE

 

  1. DEBETTE S*, VISVIKIS-SIEST S*, CHEN MH, NDIAYE NC, SONG C, DESTEFANO A, SAFA R, AZIMI NEZHAD M, SAWYER D, MARTEAU JB, XANTHAKIS V, SIEST G, SULLIVAN L, PFISTER M, SMITH H, CHOI SH, LAMONT J, LIND L, YANG Q, FITZGERALD P, INGELSSON E, VASAN RS**, SESHADRI S**. Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels. Circ Res 2011, 109(5): 554-63. *co-first authors, **co-last authors.  (P-D-C-CL-CO) - Facteur d’Impact: 9.504
  2. BUXTON JL, WALTERS RG, VISVIKIS-SIEST S, MEYRE D, FROGUEL P, BLAKEMORE AIF. Childhood obesity is associated with shorter leukocyte telomere length. J Clin Endocrinol Metab 2011; 96:1500-1505. (P-D-C-CL-CO) - Facteur d’Impact: 6.202
  3. JEANNESSON E, SIEST G, HERBERH B, ALBERTINI L, SHAHABI P, PFISTER M, VISVIKIS-SIEST S. Biological and genetic factors associated with ABCB1 and PXR expressions in PBMCs in the STANISLAS cohort. Drug Metabolism and Drug Interactions 2011; 26 (1): 27-32.  (P-D-C-CL-CO) - Facteur d’Impact: 0
  4. Barker A, Sharp S. J, Timpson NJ, Bouatia-Naji N, Warrington NM, … Ndiaye NC, … Visvikis-Siest S, Dedoussis GV, Palmer LJ, Froguel P, Davey Smith G, Ekelund U, Wareham NJ, Langenberg C. Association of genetic loci with glucose levels in childhood and adolescence. A meta-analysis of over 6,000 children. Diabetes 2011 60(6): 1805-1812. (P-D-C-CL-CO) - Facteur d’Impact: 8.784
  5. Nzietchueng R*, El Shamieh S*, Benachour H, Labat C, Herbeth B, Ndiaye NC, Masson C, Visvikis-Siest S, Benetos A. Klotho KL-VS genotype is involved in blood pressure regulation. Clin Chim Acta 2011,412(19-20): 1773-7. *co-first authors. (P-D-C-CL-CO) - Facteur d’Impact: 2.535
  6. JACQUEMONT S, REYMOND A, ZUFFEREY F, … NDIAYE NC, … VISVIKIS-SIEST S, … BLAKEMORE AI, BECKMANN JS, FROGUEL P. Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature. 2011, 478(7367): 97-102. (P-D-C-CL-CO) - Facteur d’Impact: 36.101
  7. SPELIOTES EK, YERGES-ARMSTRONG LM, WU J, … SCHADT EE, SCHWARTZ SM, SISCOVICK DS; NASH CRN; GIANT CONSORTIUM; MAGIC INVESTIGATORS, GOLD CONSORTIUM; (VISVIKIS-SIEST S in collaborators list: MAGIC INVESTIGATORS). Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits. PLoS Genet.2011 Mar; 7(3): e1001324. (P-D-C-CL-CO) - Facteur d’Impact: 8.694
  8. Eisenberg DT, Salpea KD, Kuzawa CW, Hayes MG, Humphries SE; (VISVIKIS-SIEST S in collaborators list: European Atherosclerosis Research Study II Group). Substantial Variation in qPCR Measured Mean Blood Telomere Lengths in Young Men from Eleven European Countries. Am J Hum Biol. 2011 Mar-Apr; 23(2): 228-31. (P-D-C-CL-CO)  - Facteur d’impact: 2.267
  9. Zhu H, Shyh-Chang N, Segrè AV, … Thornton JE, Triboulet R, Gregory RI; DIAGRAM CONSORTIUM; MAGIC INVESTIGATORS; (VISVIKIS-SIEST S in collaborators list: MAGIC INVESTIGATORS). The Lin28/let-7 Axis Regulates Glucose Metabolism. Cell. 2011 Sep 30; 147(1): 81-94. (P-D-C-CL-CO) - Facteur d’impact: 32.403
  10. STRAWBRIDGE RJ, DUPUIS J, PROKOPENKO I, ... , WEEDON MN, XIE W, ZETHELIUS B; DIAGRAM CONSORTIUM; GIANT CONSORTIUM; MuTHER CONSORTIUM; CARDIoGRAM CONSORTIUM; C4D CONSORTIUM; (VISVIKIS-SIEST S in collaborators list). Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes. 2011 Oct; 60(10): 2624-34. (P-D-C-CL-CO) - Facteur d’impact: 8.784

 

FI mean 2011 =11,52

 

  1. Azimi-Nezhad M, Lambert D, Ottone C, Perrin C, Chapel C, Gaillard G, Pfister M, Masson C, Tabone E, Betsou F, Meyronet D, Ungeheuer MN, Visvikis-Siest S. Influence of pre-analytical variables on VEGF gene expression and circulating protein concentrations. Biopreservation and Biobanking 2012; 10(5): 454-61 (P-D-C-CL-CO) - Facteur d’Impact: 1.294
  2. Herbeth B, Samara A, Stathopoulou M, Siest G, Visvikis-Siest S. Alcohol Consumption, Beverage Preference, and Diet in Middle-Aged Men from the STANISLAS Study. J Nutr Metab. 2012; 2012: 987243. (P-D-C-CL-CO) - Facteur d’Impact: 0
  3. Mangino M, Hwang SJ, Spector TD, Hunt SC, Kimura M, … El Shamieh S, Visvikis-Siest S, … Schork NJ, Levy D, Aviv A. Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Hum Mol Genet. 2012; 21(24): 5385-94. (P-D-C-CL-CO) - Facteur d’Impact: 7.636
  4. El Shamieh S, Ndiaye NC, Stathopoulou MG, Murray HA, Masson C, Lamont JV, Fitzgerald P, Benetos A, Visvikis-Siest S. Functional epistatic interaction between rs6046G>A in F7 and rs5355C>T in SELE modifies systolic blood pressure levels. PLoS One. 2012; 7(7): e40777. (P-D-C-CL-CO) - Facteur d’Impact: 4.092
  5. El-Sayed Moustafa JS, Eleftherohorinou H, … Visvikis-Siest S, … Froguel P, Blakemore AI, Coin LJ. Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity. Hum Mol Genet. 2012; 21 (16): 3727-38. (P-D-C-CL-CO) - Facteur d’Impact: 7.636
  6. Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N, Lohman K; GIANT Consortium; MAGIC Consortium; GLGC Consortium; (VISVIKIS-SIEST S in collaborators list: MAGIC CONSORTIUM) Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet. 2012;8(5): e1002695.. (P-D-C-CL-CO) - Facteur d’Impact: 8.694
  7. Shahabi P, Siest G, Herbeth B, Ndiaye NC, Visvikis-Siest S. Clinical necessity of partitioning of human plasma haptoglobin reference intervals by recently-discovered rs2000999. Clin Chim Acta. 2012; 413(19-20): 1618-24. (P-D-C-CL-CO) - Facteur d’Impact: 2.54
  8. Dastani Z, Hivert MF, Timpson N, … JAMES B. MEIGS , JOSEE DUPUIS, J. BRENT RICHARDS; DIAGRAM+ Consortium; MAGIC Consortium; GLGC Investigators; MuTHER Consortium; (VISVIKIS-SIEST S in collaborators list: MAGIC CONSORTIUM). Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012;8(3): e1002607. (P-D-C-CL-CO) - Facteur d’Impact: 8.694
  9. Froguel P*, Ndiaye NC*, Bonnefond A, Bouatia-Naji N, Dechaume A, Siest G, Herbeth B, Falchi M, Bottolo L, Guéant-Rodriguez RM, Lecoeur C, Langlois MR, Labrune Y, Ruokonen A, El Shamieh S, Stathopoulou MG, Morandi A, Maffeis C, Meyre D, Delanghe JR, Jacobson P, Sjöström L, Carlsson LM, Walley A, Elliott P, Jarvelin MR, Dedoussis GV, Visvikis-Siest S. A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels. PLoS One. 2012; 7(3): e32327. *co-first authors. (P-D-C-CL-CO) - Facteur d’Impact: 4.092
  10. Azimi-Nezhad M, Herbeth B, Siest G, Dadé S, Ndiaye NC, Esmaily H, Hosseini SJ, Ghayour-Mobarhan M, Visvikis-Siest S. High prevalence of metabolic syndrome in Iran in comparison with France: what are the components that explain this? Metab Syndr Relat Disord. 2012; 10(3):  181-8. (P-D-C-CL-CO) - Facteur d’Impact: 1.94
  11. Palmer ND, McDonough CW, Hicks PJ, … Rudock ME, Talbert ME, Lewis JP; DIAGRAM Consortium; MAGIC Investigators, Ferrara A, Lu L, Ziegler JT, … Visvikis-Siest S, … Peltonen L, Mooser V, Sladek R.A Genome-wide association search for type 2 diabetes genes in African Americans. PLoS One. 2012; 7(1): e29202. (P-D-C-CL-CO) - Facteur d’Impact: 4.092
  12. El Shamieh S, Herbeth B, Azimi-Nezhad M, Benachour H, Masson C, Visvikis-Siest S. Human formyl peptide receptor 1 C32T SNP interacts with age and is associated with blood pressure levels. Clin. Chim. Acta. 2012; (413): 34-8. (P-D-C-CL-CO) - Facteur d’Impact: 2.535
  13. STOLK L, PERRY JRB, ...  STATHOPOULOU MG, …  LUNETTA KL. Meta-analyses identify 13 novel loci associated with age at menopause and highlights DNA repair and immune pathways. Nat Genet 2012; 44(3): 260-268. (P-D-C-CL-CO) - Facteur d’Impact: 29.648

 

FI mean 2012 = 6,376

 

  1. Samara A, Herbeth B, Ndiaye NC, Fumeron F, Billod S, Siest G, Visvikis-Siest S. Dairy product consumption, calcium intakes, and metabolic syndrome-related factors over 5 years in the STANISLAS study. Nutrition 2013; 29(3): 519-24. (P-D-C-CL-CO) - Facteur d’Impact: 3.025
  2. Nivet-Antoine V, Labat C, El Shamieh S, Dulcire X, Cottart CH, Beaudeux JL, Zannad F, Visvikis-Siest S, Benetos A. Relationship between catalase haplotype and arterial aging. Atherosclerosis. 2013 Mar; 227(1): 100-5. (P-D-C-CL-CO) - Facteur d’impact: 3.794
  3. Bonnefond A, Saulnier PJ*, Stathopoulou MG*, Grarup N*, Ndiaye NC*, Dechaume A, Roussel R, Lantieri O, Hercberg S, Balkau B, Hansen T, Pedersen O, Froguel P, Charpentier G, Marre M, Hadjadj S, Visvikis-Siest S. What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications? PLoS One. 2013;8(2): e55921. *co-second authors (P-D-C-CL-CO) - Facteur d’Impact: 4.092
  4. Stathopoulou MG*, Bonnefond A*, Ndiaye NC*, Azimi-Nezhad M, El Shamieh S, Saleh A, Rancier M, Siest G, Lamont J, Fitzgerald P, Visvikis-Siest S. A common variant highly associated with plasma VEGFA levels also contributes to the variation of both LDL-C and HDL-C. J Lipid Res. 2013; 54(2): 535-41. *co-first authors. (P-D-C-CL-CO) - Facteur d’Impact: 5.559
  5. Ndiaye NC, Shamieh SE, Stathopoulou MG, Siest G, Tsai MY, Visvikis-Siest S. Epistatic study reveals two genetic interactions in blood pressure regulation. BMC Med Genet. 2013; 14(1): 2. (P-D-C-CL-CO) - Facteur d’Impact: 2.33
  6. Azimi-Nezhad M*, Stathopoulou MG*, Bonnefond A, Rancier M, Saleh A, Lamont J, Fitzgerald P, Ndiaye NC, Visvikis-Siest S. Associations of vascular endothelial growth factor (VEGF) with adhesion and inflammation molecules in a healthy population. Cytokine 61 (2013) 602-607. *co-first authors. (P-D-C-CL-CO) - Facteur d’Impact: 3.019
  7. Barbaud A, Waton J, Herbeth B, Bursztejn A.C, Bollaert M, Schmutz J.L, Guéant-Rodriguez R.M, Namour F, Guéant J.L, Aimone-Gastin I. Comparison of cytokine gene polymorphism in drug-induced maculopapular eruption, urticaria and drug reaction with eosinophilia and systemic symptoms (DRESS). (P-D-C-CL-CO)  - Facteur d’Impact: 3.105
  8. Stathopoulou MG, Monteiro P*, Shahabi P*, Penas-Lledo E, El Shamieh S, Silva Santos L, Thilly N, Siest G, Llerena A, Visvikis-Siest S. Newly identified synergy between Clopidogrel and calcium-channel blockers for blood pressure regulation possibly involves CYP2C19 rs4244285. Int J Cardiol. 2013 Oct 3; 168(3): 3057-8. *co-second authors. (P-D-C-CL-CO) - Facteur d’Impact: 7.078
  9. Shahabi P, Siest G, Herbeth B, Lambert D, Masson C, Hulot J.S, Bertil S, Gaussem P*, Visvikis-Siest S*. Influence of Genetic Variations on Levels of Inflammatory Markers of Healthy Subjects at Baseline and One Week after Clopidogrel Therapy; Results of a Preliminary Study. Int. J. Mol. Sci. 2013, 14 16402-16413. *co-last authors (P-D-C-CL-CO) - Facteur d’Impact: 2.732
  10. EVANS DM, BRION MJ, PATERNOSTER L, … WHITFIELD JB, MEDLAND SE, MONTGOMERY GW; GIANT CONSORTIUM; CRP CONSORTIUM; TAG CONSORTIUM; (VISVIKIS-SIEST S in collaborators list). Mining the human phenome using allelic scores that index biological intermediates. PLoS Genet. 2013; e1003919. PMID: 24204319. (P-D-C-CL-CO) - Facteur d’Impact: 8.167
  11. MAUBARET CG, SALPEA KD, ROMANOSKI CE, … ERIKSSON P, TALMUD PJ, HUMPHRIES SE; The EARSII CONSORTIUM; (VISVIKIS-SIEST S in collaborators list). Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease. PLoS One. 2013 Dec 12;8(12): e83122. (P-D-C-CL-CO) - Facteur d’Impact: 3.534
  12. Vimaleswaran KS, Berry DJ, Lu C, … , Whittaker JC, Hingorani AD, Hyppönen E; The Genetic Investigation of Anthropometric Traits (GIANT) CONSORTIUM (VISVIKIS-SIEST S in collaborators list: GIANT CONSORTIUM). Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med. 2013; 10(2): e1001383. (P-D-C-CL-CO) - Facteur d’Impact: 16.974

 

FI mean 2013= 5,28

 

  1. Falchi M, El-Sayed Moustafa JS, Takousis P, … Visvikis-Siest S, … Pattou F, Spector TD, Froguel P. Low number of copies of the salivary amylase gene predisposes to obesity. Nat. Genet. 2014 May; 46(5): 492-7. (P-D-C-CL-CO) - Facteur d’Impact: 29,352
  2. Shahabi P, Siest G, Meyer U, Visvikis-Siest S. Human Cytochrome Epoxygenases: Variability in Expression and Role in inflammation-related Disorders. Pharmacol Ther. 2014 Nov, 144(2): 134-161. (P-D-C-CL-CO) - Facteur d’Impact: 9,723
  3. CLEMENT B, YUILLE M, ZALTOUKAL K, … BRECHOT C, HOFMAN P, DAGHER G; EU-US Expert Group on cost recovery in biobanks; (VISVIKIS-SIEST S and GODJO T in collaborators list). Public biobanks: calculation and recovery of costs. Sci Transl Med. 2014 Nov, 5; 6 (261): 261fs45. (P-D-C-CL-CO) - Facteur d’Impact: 15,843

 

FI mean 2014=18,306

 

  1. LOCKE AE, KAHALI B, BERNDT SI, ... HIRSCHHORN JN, LOOS RJ, SPELIOTES EK; (STATHOPOULOU MG in collaborators list). Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015 Feb 12;518(7538):197-206.. (P-D-C-CL-CO) - Facteur d’Impact: 42.35
  2. SHUNGIN D, WINKLER TW, CROTEAU-CHONKA DC, ... MORRIS AP, LINDGREN CM, MOHLKE KL; (STATHOPOULOU MG in collaborators list). New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015 Feb 12;518(7538):187-96. (P-D-C-CL-CO ) - Facteur d’Impact: 42.35
  3. STATHOPOULOU MG, PETRELIS AM, BUXTON JL, FROGUEL P, BLAKEMORE AIF, VISVIKIS-SIEST S. Genetic determinants of leukocyte telomere length in children: a neglected and challenging field. Paediatr Perinat Epidemiol. 2015 Mar; 29(2): 146-50. (P-D-C-CL-CO) - Facteur d’Impact: 2.81
  4. SHAHABI P*, CUISSET T*, STATHOPOULOU MG, MORANGE PE, GROSDIDIER C, HERBETH B, SIEST G, ALESSI MC**, VISVIKIS-SIEST S**. Genetic-determined Low Response to Thienopyridines is Associated with Higher Systemic Inflammation in Smokers. Pharmacogenomics 2015, Apr; 16(5): 459-69. *co-first authors. **co-last authors. (P-D-C-CL-CO) - Facteur d’Impact: 3.43
  5. GOODARZ D*, SAMAN F*, YUAN L, … LEANNE MR, MOHAMMED KA, MAJID E; (NDIAYE NC and VISVIKIS-SIEST S in collaborators list). Impact of diabetes definition on global surveillance of diabetes prevalence and diagnosis: pooled analysis of 96 population-based studies with 331,000 participants. The Lancet Diabetes & Endocrinology (www.thelancet.com/diabetes-endocrinology). Published online June 22, 2015. *co-first authors. (P-D-C-CL-CO) - Facteur d’Impact: 9.185 
  6. SALEH A*, STATHOPOULOU MG*, DADE S, NDIAYE NC, AZIMI-NEZHAD M, MURRAY H, MASSON C, LAMONT J, FITZGERALD P, VISVIKIS-SIEST S. Angiogenesis related genes NOS3, CD14, MMP3 and IL4R are associated to VEGF gene expression and circulating levels in physiological conditions. BMC Medical Genetics. 2015 Oct 5;16: 904, 0234-6. *co-first authors. (P-D-C-CL-CO) - Facteur d’Impact: 2.45

 

FI mean 2015 =17,095

 

  1. CHOI SH*, RUGGIERO D*, SORICE R*, SONG C, NUTILE T, VERNON SMITH A, PINA CONCAS M, TRAGLIA M, BARBIERI C, NDIAYE NC, STATHOPOULOU MG, LAGOU V, BATTISTA MAESTRALE G, SALA C, E DEBETTE SA, KOVACS P, LIND L, LAMONT J, FITZGERALD P, TÖNJES A, GUÐNASON V, INGELSSON E, TONIOLO D, PIRASTU M, BELLENGUEZ C, VASAN RS, LEUTENEGGER AL, DESTEFANO AL, VISVIKIS-SIEST S, SESHADRI S**, CIULLO M**. Six novel loci associated with circulating VEGF levels identified by a meta-analysis of genome-wide association studies. PLoS Genet. 2016 Feb 24;12(2):e1005874. *co-first authors. **co-last authors. (P-D-C-CL-CO) - Facteur d’Impact: 8.167
  2. ZAABER I*, RANCIER M*, STATHOPOULOU M, SALEH A, MARMOUCH H, MASSON C, MURRAY H, KURTH MJ, LAMONT J, FITZGERALD P, MAHJOUB S, SAID K, BEL HADJ JRAD TENSAOUT B, MESTIRI S, VISVIKIS-SIEST S. Plasma VEGF- related polymorphisms are implied in autoimmune thyroid diseases. Autoimmunity 2016 Jun;49(4):229-35. *co-first authors. (P-D-C-CL-CO) - Facteur d’Impact: 2.714
  3. DI CESARE M, BENTHAM J, STEVENS GA, … STATHOPOULOU MG, … VISVIKIS-SIEST S, …  ZHU D, ZIMMERMANN E, ZUÑIGA CISNEROS J; NCD Risk Factor Collaboration (NCD-RisC). Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. The Lancet 2016 Apr 2;387(10026):1377-96. (P-D-C-CL-CO)  - Facteur d’Impact: 45.217
  4. ZHOU B, LU Y, HAJIFATHALIAN K, … NDIAYE NC,STATHOPOULOU MG, … VISVIKIS-SIEST S, … ZHAO W, ZHENG Y, ZUÑIGA CISNEROS J; NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in diabetes since 1980: pooled analysis of 751 population-based measurement studies with over 4.4 million participants. Lancet. 2016 Apr 9;387(10027):1513-30. doi: 10.1016/S0140-6736(16)00618-8. Epub 2016 Apr 6. (P-D-C-CL-CO) - Facteur d’Impact: 45.217.
  5. RANCIER M*, ZAABER I*, STATHOPOULOU MG, CHATELIN J, SALEH A, EL SHAMIEH S, MARMOUCH H, MASSON C, MURRAY H, KURTH MJ, LAMONT J, FITZGERALD P, MAHJOUB S, SAID K, BEL HADJ JRAD TENSAOUT B, MESTIRI S, VISVIKIS-SIEST S. Pro- and anti-angiogenic VEGF mRNAs in autoimmune thyroid diseases.  Autoimmunity 2016 Aug 5:1-7. 2016 Sep;49(6):366-372 *co-first authors. (P-D-C-CL-CO) - Facteur D’impact: 2.714
  6. BENTHAM J, DI CESARE M, STEVENS GA, … STATHOPOULOU MG, … VISVIKIS-SIEST S, … ZHAO W, ZHENG Y, ZUÑIGA CISNEROS J. A century of trends in adult human height. NCD Risk Factor Collaboration (NCD-RisC). Elife. 2016 Jul 26;5. pii: e13410. doi: 10.7554/eLife.13410. (P-D-C-CL-CO) - Facteur D’impact: 8.303
  7. Gbadoe KM, Berdouzi N, Aguiñano AA, Ndiaye NC, Visvikis-Siest S. Cardiovascular diseases-related GNB3 C825T polymorphism has a significant sex-specific effect on serum soluble E-selectin levels. J Inflamm (Lond). 2016 Dec 9;13:39.

FI mean 2016 = 18.722

 

  1. Xie T, Stathopoulou MG, de Andrés F, Siest G, Murray H, Martin M, Cobaleda J, Delgado A, Lamont J, Peñas-LIedó E, LLerena A, Visvikis-Siest S. VEGF-related polymorphisms identified by GWAS and risk for major depression. Transl Psychiatry. 2017 Mar 7;7(3):e1055. doi: 10.1038/tp.2017.36.

 

 

FI mean 2017 =

 

     2/ PUBLICATIONS DE REVUES DANS DES JOURNAUX DE SPECIALITE A COMITE DE LECTURE

 

  1. Albertini L, Siest G, Jeannesson E, Visvikis-Siest S. Availability of pharmacogenetic and pharmacogenomic information in anticancer drug monographs in France: personalized cancer therapy. Pharmacogenomics. 2011 May; 12(5): 681-91. (P-D-C-CL-CO) - Facteur d’Impact: 3.893
  2. Ndiaye NC*, Azimi Nehzad M*, El Shamieh S*, Stathopoulou MG*, Visvikis-Siest S*. Cardiovascular diseases and genome-wide association studies. Clin Chim Acta. 2011; 412(19-20): 1697-701. *equal contribution. (P-D-C-CL-CO) - Facteur d’Impact: 2.535
  3. Visvikis-Siest S, Stathopoulou MG, Ndiaye NC. Common mutations and polymorphisms predicting adverse cardiovascular events: current view. Pharmacogenomics. 2012; 13(16): 1875-8. (P-D-C-CL-CO) - Facteur d’Impact: 3.974
  4. El Shamieh S, Visvikis-Siest S. Genetic biomarkers of hypertension and future challenges integrating epigenomics. Clin Chim Acta. 2012; 414: 259-65. (P-D-C-CL-CO) - Facteur d’Impact: 2.54
  5. Shahabi P, Siest G, Visvikis-Siest S. Clinical interest of point-of-care pharmacogenomic testing: clopidogrel behind warfarin. Pharmacogenomics 2012; 13(11): 1215-8. (P-D-C-CL-CO) - Facteur d’Impact: 3.974
  6. LIPPI G, GILLERY P, KAZMIERCZAK S, LACKNER KJ, MELICHAR B, SIEST G, WHITFIELD JB, JAHNKE H, PLEBANI M. Clinical Chemistry and Laboratory Medicine: progress and new challenges for our 50-year-old journal. Clin. Chem. Lab. Med. 2013 Jan; 51(1): 5-7. (P-D-C-CL-CO) - Facteur d’impact: 2.955
  7. Siest G, Henny J, Gräsbeck R, Wilding P, Petitclerc C, Queralto Joseph M, Hyltoft Petersen Peter. The theory of reference values: an unfinished symphony. Clin Chem Lab Med 2013:51(1): 47-64. (P-D-C-CL-CO) - Facteur d’Impact: 2.955
  8. Shahabi P, Siest G, Visvikis-Siest S. Influence of inflammation on cardiovascular protective effects of cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids Drug Metab Rev. 2014 Feb; 46(1): 33-56. (P-D-C-CL-CO) - Facteur d’impact: 5.538
  9. VISVIKIS-SIEST S, STATHOPOULOU MG. Beyond genome-wide association studies: identifying variants using -omics approaches. Pers Med; Nov 2015 (in press). (P-D-C-CL-CO) - Facteur d’Impact: 1.336
  10. Chatelin J, Stathopoulou MG, Arguinano AA, Xie T, Visvikis-Siest S. Pharmacogenomic challenges in cardiovascular diseases: examples of drugs and considerations for future integration in clinical practice. Curr Pharm Biotechnol. 2017 Jan 23. [Epub ahead of print]

 

 

  1. PUBLICATIONS EFFECTUEES DANS LE CADRE DE CONGRES INTERNATIONAUX / ABSTRACTS DANS DES JOURNAUX A COMITE DE LECTURE

 

  1. Chambers, John C, Zhang, ... Visvikis-Siest S, ... Järvelin MR, Elliott P, Kooner JS. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet. 2011; 43(11): 1129-31. (P-D-C-CL-CO) - Facteur d’Impact: 29.648
  2. Siest G, Azimi Nezhad M, Bagrel D, El Shamieh S, Lambert D, Ndiaye NC, Shahabi P, Visvikis-Siest S. Functional genomics towards personalized health care and systems medicine. 5th “Biologie Prospective” Santorini Conference, Santorini Island, Greece, September 30 – October 2, 2010. Pers Med 2011; 8(3): 227-242. (P-D-C-CL-CO) - Facteur d’Impact: 1.336
  3. MANOLOPOULOS VG, DECHAIRO B, HURIEZ A, KÜHN A, LLERENA A, VAN SCHAIK RH, YEO KTJ, RAGIA G, SIEST G. Pharmacogenomics and personalized medicine in clinical practice: Round table report. 5th Biologie Prospective Santorini Conference, Island of Santorini, Greece, 30th September – 2nd October 2010. Pharmacogenomics 2011; 12 (5): 597-610. (P-D-C-CL-CO) - Facteur d’Impact: 4.229
  4. Visvikis-Siest S. VEGF in Pharmacogenomics. Drug. Metab. Drug. Interact. 2013; 28(1) A5. (P-D-C-CL-CO) - Facteur d’Impact: 0
  5. Visvikis-Siest S. The importance of VEGF in pharmacogenomics. Drug. Metab. Drug. Interact. 2013; 28(3) A18. (P-D-C-CL-CO) - Facteur d’Impact: 0
  6. Siest G, Ndiaye NC, El Shamieh S, Shahabi P, Stathopoulou Mg, saleh AS, Godjo T, Albertini l, Visvikis-Siest S. Systems biology and personalized medicine science and translation. 6th Biologie Prospective conference Santorini Island, Greece, 30 September -2 October2012. Pharmacogenomics (2013) 14(16), 1953-1964. (P-D-C-CL-CO) - Facteur d’impact: 4.229
  7. Siest G, Medeiros r, Melichar B, Stathopoulou M, Van Schaik RHN, Cacabelos R, Meier Abt P, Monteiro C, Gurwitz D, Queiroz J, Mota-Filipe H, Ndiaye NC, Visvikis-Siest S. Conference Scene – Pharmacogenomics: From cell to clinic (Part 1). Pharmacogenomics (2014) 15(5), 593-599. (P-D-C-CL-CO) - Facteur d’impact: 4.229
  8. Siest G, Medeiros r, Melichar B, Stathopoulou M, Van Schaik RHN, Cacabelos R, Meier Abt P, Monteiro C, Gurwitz D, Queiroz J, Mota-Filipe H, Ndiaye NC, Visvikis-Siest S. Conference Scene – Pharmacogenomics: From cell to clinic (Part 2). Pharmacogenomics (2014) 15(6), 739-744. (P-D-C-CL-CO) - Facteur d’impact: 4.229
  9. Siest G, Auffray C, Taniguchi N, Ingelman Sundberg M, Murray H, Visvikis-Siest S, Ansari M, Marc J,  Jacobs P, Meyer U, Van Schaik RHN, Müller MM,  Wevers  RA, Simmaco Maurizio, Kussmann M,  Manolopoulos VG, Alizadeh BZ, Beastall  G, Németh G. Conference scene: Systems medicine, personalized health and therapy. Pharmacogenomics. 2015 (ISSN 1462-2416). (P-D-C-CL-CO) - Facteur d’impact: 4.229

 

  1. PUBLICATIONS DIDACTIQUES - RECOMMENDATIONS

 

  1. Visvikis S .The use of multiplex assays for determining predisposition to hypertension. Clin Chem Lab Med. 2011. 49: 182-2. (P-D-C-CL-CO) 
  2. Albertini L, Siest G, Shahabi P, Visvikis-Siest S. Need for pharmacogenomics information also for generic medications: Recommandation of the European Society of Pharmacogenomics and Theranostics (ESPT). Drug Metabol Drug Interact 2012; 27(2): 119. (P-D-C-CL-CO) 
  3. SIEST G. Pharmacogenomics from cell to clinic. Drug Metab Drug Interact 2013; 28 (3): 133. (P-D-C-CL-CO) 
  4. SIEST G, SCHALLMEINER E. Pharmacogenomics and Theranostics in practice – A summary of the Euromedlab-ESPT (The European Society of Pharmacogenomics and Theranostics) satellite symposium. May 2013. EjIFCC Clin Chem Lab Med 2013 Vol; 24, n. 3-4. (P-D-C-CL-CO) 
  5. Siest G. Systems Medicine, Stratified Medicine, Personalized Medicine but not precision medicine. Drug Metab. Drug Interact. 2014; 26(1): 1-2. (P-D-C-CL-CO) 
  6. Ndiaye NC. Systems Medicine in the era of “Big Data”: a game-changer for Personalized Medicine? Drug Metab. Drug Interact. 2014; 29(3): 127. (P-D-C-CL-CO)
  7. Siest G, Fournel-Gigleux S, Magdalou J. CYP 2C19 and UDP-glucuronosyltransferases not only for drugs, but also for endobiotics. Drug Metab. Drug Interact. 2014; 29(4): 207-9. (P-D-C-CL-CO)
  8. SIEST G. From DMDI "Drug Metabolism and Drug Interactions" to DMPT "Drug Metabolism and Personalized Therapy". Drug Metabol Personal Ther. 2015 Mar 1; 30(1): 1. doi: 10.1515/dmdi-2015-0039. (P-D-C-CL-CO)
  9. MALENTACCHI F, MANCINI I, BRANDSLUND I, VERMEERSCH P, SCHWAB M, MARC J, VAN SCHAIK R.H.N, SIEST G, THEODORSSON E, PAZZAGLI M, DI RESTA C, on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) – European Society of Pharmacogenomics and Personalised Therapy (ESPT) Joint Working Group on Personalized Laboratory Medicine (WG-PLM). Is laboratory medicine ready for the era of personalized medicine? A survey addressed to laboratory directors of hospitals/academic schools of medicine in Europe. Clin Chem Lab Med 2015 Jun;53(7):981-8. (P-D-C-CL-CO)

 

 

 

  1. Publications Nationales (ACLL)

 

  1. SIEST G. Les 70 ans des ABC : témoignages… Ann. Biol. Clin. 2012; 70 (5): 509. (P-D-C-CL-CO)
  2. VISVIKIS-SIEST S. BIOINFORMATIQUE- Quand le labo se fait virtuel. Sciences et Santé. 2015 Juillet – Août; 26: 2. (P-D-C-CL-CO)
  3. SIEST G, VISVIKIS-SIEST S. La Pharmacogénomique, meilleur exemple de médecine personnalisée. Hegel. 2016 Vol. 6 N° 1 : 10-21. (P-D-C-CL-CO)
  4. VISVIKIS-SIEST S. BIOINFORMATIQUE- Quand le labo se fait virtuel. Sciences et Santé. 2015 Juillet – Août; 26: 2. (P-D-C-CL-CO)

 

 

 

 

 

  1. Conférences invitées (INV)

 

  1. SIEST G. Pharmacogenomics of clopidogrel and other antiplatelet agents: A major issue in current cardiology. 3rd GoldenHelix Pharmacogenomics Day, Alexandropoulis, Grèce, 8 avril 2011. (P-D-C-CL-CO)
  2. VISVIKIS-SIEST S. The use of multiplex assays for determining predisposition to Hypertension. 2ndCongress of the European Society of Predictive Medicine. Berlin, Allemagne, 14-15 mai 2011. (P-D-C-CL-CO)
  3. SIEST G. ESPT goals and drug safety. 4th International Conference on Pharmaceutical Sciences”, Bled, Slovénie, 1er octobre 2011. (P-D-C-CL-CO)
  4. VISVIKIS-SIEST S. Biobanks and Research in Pharmacogenomics. European Master Degree Programme in Clinical Research, University ofExtremadura, Badadoz, Spain, 30 October 2011. (P-D-C-CL-CO)
  5. VISVIKIS-SIEST S. Influence of pre-analytical variables on VEFG-A gene expression and circulating protein concentrations. ESBB meeting, Marseille 16-19 Novembre 2011. (P-D-C-CL-CO)
  6. SIEST G. Pharmacogenomics of Cardiovascular Drugs: Integration of Genomics, Transcriptomics and Biomarkers for a Systems Biology Approach. International Symposium on Systems Biology in Physiology/Medicine, New Dehli, Inde, 13 décembre 2011. (P-D-C-CL-CO)
  7. SIEST G. Future Development and Perspectives of Pharmacogenomics and Theranostics. ArabMedLab 2012 - 13th Arab Congress of Clinical Biology (AFCB) and 12th Moroccan Congress of Clinical Chemistry and Laboratory Medicine, Marrakech, Marroc, 2-5 Mai 2012. (P-D-C-CL-CO)
  8. VISVIKIS-SIEST S. Biobanking in personalized medicine. 13th Arab Congress of Clinical Biology and  12th Moroccan Congress of Clinical Chemistry and Laboratory Medicine, Marrakech, Maroc, 2-5 Mai 2012. (P-D-C-CL-CO)
  9. SIEST G. Cardiovascular drugs pharmacogenomics: Interest of eventual antiinflammatory side effects. 4th annual Translational Medicine Conference (Inflammatory Processes and Cardiovascular Disease), Londres, Royaume Unis, 10-11 Mai 2012. (P-D-C-CL-CO)
  10. SIEST G. Interest of a system biology approach for cardiovascular drugs pharmacogenomics. The 1st International meeting of Research an innovation in the cardiovascular field, Sousse, Tunisie, 27-28 Juin 2012. (P-D-C-CL-CO)
  11. VISVIKIS-SIEST S. Genetic etiology of cardiovascular diseases: GWAS designs of associated quantitative traits. Les 9 èmes Journées Tuniso Européennes de Cardiologie Pratique, Sousse, Tunisie, 28-30 juin 2012. (P-D-C-CL-CO)
  12. VISVIKIS-SIEST S. Integrative Studies of VEGF genetic variants. Symposium Biointelligence, Nice, France,  01-04 Juillet 2012. (P-D-C-CL-CO)
  13. SIEST G. Pharmacogenomics: Looking to the past, moving towards the future, 5th APEF Scientific Congress « Pharmacogenomics: Luxury or Necessity? », Porto, Portugale, 11 Octobre 2012. (P-D-C-CL-CO)
  14. SIEST G. IFCC and Personalized Laboratory Medicine, IFCC General Conference 2012 – IFCC in its 60th Year– Kuala Lumpur, 19 Novembre 2012. (P-D-C-CL-CO)
  15. VISVIKIS-SIEST S. Gene-environment interactions and missing heritability. 3rd Congress of the European Society of Predictive Medicine, Riolo Terme Italie, 9-10 mars 2013. (P-D-C-CL-CO)
  16. SIEST G. The Impact of Genetic Factors on Lipoproteins and Inflammatory Markers Variations. Symposium Lipid und Vitamine, Homburg, Allemagne, 12 April 2013. (P-D-C-CL-CO)
  17. VISVIKIS-SIEST S. A genome-wide association study identifies a strong genetic determinant of circulating haptoglobin levels. Workshop on Haptoglobin and related proteins: Biology, Pathology, Genetics and Clinical applications University College London, Londres Royaume Uni, 19 Avril 2013. (P-D-C-CL-CO)
  18. SIEST G. The Quality of Molecular Methods in the age of Personalized Medicine Session IV : Needs/Requirements from Societies/Industry - ESPT Point of View.– EUROMEDLAB – Milan, Italie, 18 May 2013. (P-D-C-CL-CO)
  19. VISVIKIS-SIEST S. Gene-gene interactions can modify the effect of a SNP associated with Blood Pressure Levels. Educational Workshop in collaboration with Randox Laboratories. Euromedlab. Milan, Italie, 19-23 mai 2013. (P-D-C-CL-CO)
  20. VISVIKIS-SIEST S. VEGF in Pharmacogenomics. ESPT Satellite meeting: Pharmacogenomics and Theranostics in Practice”, Florence, Italie, 24 mai 2013. (P-D-C-CL-CO)
  21. SIEST G. Pharmacogenomics of Clopidogrel, - ESPT Satellite meeting of EUROMEDLAB- Florence, Italie, 24 May 2013. (P-D-C-CL-CO)
  22. VISVIKIS-SIEST S. Missing heritability in Blood Pressure regulation and Hypertension and Gene-Gene-Environment Interactions. Satellite Symposium to the 23rd European Meeting on Hypertension Università Degli Studi di Padovard, Padoue, Italie, 19 Juin 2013. (P-D-C-CL-CO)
  23. SIEST G. ESPT structure and organisation, Rome, Italie, 9 June. (P-D-C-CL-CO)
  24. VISVIKIS-SIEST S. VEGF: an example of a potential systems medicine new biomarker - 2ème Summer School ESPT “Pharmacogenomics and other omics leading to personalized medicine: Established and emerging scientific, clinical and ethical aspects”, Rome, Italie du 09 au 14 juin 2014. (P-D-C-CL-CO)
  25. SIEST G. Pharmacogenomics of Cardiovascular Drugs – The Example of Thiénopyridines , Istanbul, Turquie, 23 June 2014. (P-D-C-CL-CO)
  26. VISVIKIS-SIEST S. Time to reverse GWAS! Phenome-wide association studies. – « Systems Medicine, Personalized Health and Therapy », Santorini, Grece, 25 -27 septembre 2014. (P-D-C-CL-CO)
  27. VISVIKIS-SIEST S. VEGF, a potential biomarker in Personalized Health. – « Systems Medicine, Personalized Health and Therapy », Santorini, Grece, 25 -27 septembre 2014. (P-D-C-CL-CO)
  28. VISVIKIS-SIEST S. VEGF: a potential biomarker for Personalized Medicine. - 5th World Gene Convention-2014 (WGC-2014), Haikou, Hainan, Chine, 13-16 novembre 2014. (P-D-C-CL-CO)
  29. SIEST G. Pharmacogenomics and Systems Medicine - Hainan, Chine, 14 November 2014. (P-D-C-CL-CO)
  30. SIEST G. Pharmacogenomics and Personalized Medicine - Haikou, Chine, 19 November 2014. (P-D-C-CL-CO)
  31. SIEST G. Pharmacogenomics: From Laboratory Data to Clinic.  Odense, Denmark, 14 Janvier 2015. (P-D-C-CL-CO)
  32. VISVIKIS-SIEST S. Drug - Drug interactions in Cardiovascular Pharmacotherapeutics. – SYMPOSIUM: “ADVANCES IN PREDICTIVE & PERSONALIZED MEDICINE”; “Bridging the Nations in Istanbul: Personalized & Predictive Medicine in Turkey, Istanbul, Turquie, 1-3 avril 2015. (P-D-C-CL-CO)
  33. SIEST G. ESPT: The European Research Strategy for Pharmacogenomics & Personalised Medicine, Istanbul, Turquie, 2 April 2015. (P-D-C-CL-CO)
  34. SIEST G. Pharmacogenetics and Personalized Therapeutics Networking in Europe, Madrid, Spain, 16 April 2015. (P-D-C-CL-CO)
  35. VISVIKIS-SIEST S. VEGF, a potential biomarker for systems medicine. –EUROMEDLAB Paris, France, 21-25 juin 2015. (P-D-C-CL-CO)
  36. VISVIKIS-SIEST S. The VEGF clinical implementation pathway Genomics of VEGF
 nnd Diseases Prediction. ESPT- 2015 -Third Conference
Integration of Pharmacogenomics in clinical decision support, Budapeste, Hungrie,  8 October 2015. (P-D-C-CL-CO)
  37. VISVIKIS-SIEST S. Marie Skłodowska-Curie Actions Research and Innovation Staff Exchange (RISE) Call: H2020-MSCA-RISE-2015: Mastiha treatment for Healthy obese with NAFLD diagnosis
    MAST4HEALTH”, Atelier ITN / RISE organisé par le PCN AMSC, Paris, France, 14 Octobre 2015. (P-D-C-CL-CO)
  38. VISVIKIS-SIEST S. VEGF, a potential biomarker for systems medicine. ''Cardiovascular Health: From knowledge translation to application: A GLOBAL PERSPECTIVE FROM NEW TECHNOLOGIES TO PREVENTION'' - symposium organise par le consulat Général de France et la faculté de la santé à "York University" -, Toronto, Canada, 5 Novembre 2015. (P-D-C-CL-CO)
  39. SIEST G. Pharmacogenomics and personalised médicine - ESPT involvement, Laval, Québec / Montréal Canada, 6 Novembre 2015. (P-D-C-CL-CO)
  40. VISVIKIS-SIEST S. VEGF, a potential biomarker for systems medicine. BioFIT, Strasbourg, France, 2 Decembre 2015. (P-D-C-CL-CO)
  41. G. SIEST. Pharmacogenomics Pharmacogenomics and stratified health and medicine. The ESPT organisation. 12 December, 2015. (P-D-C-CL-CO)
  42. VISVIKIS-SIEST S. VEGF: biomarqueur potentiel de taxonomie de pathologies chroniques. Centre de recherche d’immunologie et d’hématologie de Strasbourg, Strasbourg, France, 6 janvier 2016. (P-D-C-CL-CO)
  1. Publications Hors Unité (PHU)

 

STATHOPOULOU Maria

  1. Stathopoulou MG, Dedoussis GVZ, Trovas G, Theodoraki EV, Katsalira A, Hammond N, Deloukas P, Lyritis GP. The role of vitamin D receptor gene polymorphisms in the bone mineral density of Greek postmenopausal women with low calcium intake. J Nutr Biochem 2011;22(8):752-7. (P-D-C-CL-CO)

 

XIE Ting

  1. Romero NB, Xie T, Malfatti E, Schaeffer U, Böhm J, Wu B, Xu F, Boucebci S, Mathis S, Neau JP, Monnier N, Fardeau M, Laporte J. Autosomal dominant Central Core congenital myopathy caused by a mutation in the MYH7 gene. J Neurol Neurosurg Psychiatry. 2014 Oct;85(10):1149-52. (P-D-C-CL-CO)
  2. Nsango SE, Pompon J, Xie T, Rademacher A, Fraiture M, Thoma M, Awono-Ambene PH, Moyou RS, Morlais I, Levashina EA. Wounding-induced immune responses control Plasmodium falciparum development in Anopheles gambiaes mosquitoes. J Biol Chem. 2013 May 31;288(22):16145-54. (P-D-C-CL-CO)
  3. Chatelin J, Stathopoulou MG, Arguinano AA, Xie T, Visvikis-Siest S. Pharmacogenomic challenges in cardiovascular diseases: examples of drugs and considerations for future integration in clinical practice. Curr Pharm Biotechnol. 2017 Jan 23. [Epub ahead of print]
  4. Xie T, Stathopoulou MG, de Andrés F, Siest G, Murray H, Martin M, Cobaleda J, Delgado A, Lamont J, Peñas-LIedó E, LLerena A, Visvikis-Siest S. VEGF-related polymorphisms identified by GWAS and risk for major depression. Transl Psychiatry. 2017 Mar 7;7(3):e1055. doi: 10.1038/tp.2017.36.

 

ARGUINANO Alex-Ander

  1. Gbadoe KM, Berdouzi N, Aguiñano AA, Ndiaye NC, Visvikis-Siest S. Cardiovascular diseases-related GNB3 C825T polymorphism has a significant sex-specific effect on serum soluble E-selectin levels. J Inflamm (Lond). 2016 Dec 9;13:39.

 

CHATELIN Jérôme

  1. Collet A, Chatelin J, Agopiantz M, Valduga M, Bonnet C, Allou L, Lambert L, Gospodaru RN, Weryha G, Jonveaux P.  [An adult patient with 49, XXXXY syndrome: further clinical and biological delineation]. Ann Biol Clin (Paris). 2014 May-Jun;72(3):371-7. (P-D-C-CL-CO)
  2. Pruna L, Chatelin J, Pascal-Vigneron V, Kaminsky P. Regional body composition and functional impairment in patients with myotonic dystrophy. Muscle Nerve. 2011 Oct;44(4):503-8. (P-D-C-CL-CO)

 

KLEIN Marc

  1. Agopiantz M, Elhanbali O, Demore B, Cuny T, Demarquet L, Ndiaye C, Barbe F, Brunaud L, Weryha G, Klein M. Thyroid side effects prophylaxis in front of nuclear power plant accidents. Ann Endocrinol (Paris). 2016 Jan 29. pii: S0003-4266(15)01134-8. (P-D-C-CL-CO)
  2. Diédhiou D, Cuny T, Sarr A, Norou Diop S, Klein M, Weryha G. Efficacy andsafety of denosumab for the treatment of osteoporosis: A systematic review. Ann Endocrinol (Paris). 2015 Dec;76(6):650-7. (P-D-C-CL-CO)
  3. Nomine-Criqui C, Brunaud L, Germain A, Klein M, Cuny T, Ayav A, Bresler L. Robotic lateral transabdominal adrenalectomy. J Surg Oncol. 2015 Sep;112(3):305-9. (P-D-C-CL-CO)
  4. Agopiantz M, Corbonnois P, Sorlin A, Bonnet C, Klein M, Hubert N, Pascal-Vigneron V, Jonveaux P, Cuny T, Leheup B, Weryha G. Endocrine disorders in Woodhouse-Sakati syndrome: a systematic review of the literature. J Endocrinol Invest. 2014 Jan;37(1):1-7. (P-D-C-CL-CO)
  5. Klein M, Brunaud L, Weryha G. [The thyroid nodules revisited]. Rev Prat. 2012 Mar;62(3):389-91. French. PubMed PMID: 22515002. (P-D-C-CL-CO)
  6. Renard E, Langbour-Remy C, Klein M, Le Bouc Y, Weryha G, Cuny T. Severe hypoglycemia with "Big"-IGF-2 oversecretion by a giant phyllode tumor of the breast: a rare case of non-islet cell tumor-induced hypoglycemia (NICTH). Ann Endocrinol (Paris). 2012 Nov;73(5):488-91. (P-D-C-CL-CO)

 

WERYHA Georges

  1. Agopiantz M, Elhanbali O, Demore B, Cuny T, Demarquet L, Ndiaye C, Barbe F, Brunaud L, Weryha G, Klein M. Thyroid side effects prophylaxis in front of nuclear power plant accidents. Ann Endocrinol (Paris). 2016 Jan 29. pii: S0003-4266(15)01134-8. (P-D-C-CL-CO)
  2. Diédhiou D, Cuny T, Sarr A, Norou Diop S, Klein M, Weryha G. Efficacy andsafety of denosumab for the treatment of osteoporosis: A systematic review. Ann Endocrinol (Paris). 2015 Dec;76(6):650-7. (P-D-C-CL-CO)
  3. Thevenon J, Bourredjem A, Faivre L, Cardot-Bauters C, Calender A, Le Bras M, Giraud S, Niccoli P, Odou MF, Borson-Chazot F, Barlier A, Lombard-Bohas C, Clauser E, Tabarin A, Pasmant E, Chabre O, Castermans E, Ruszniewski P, Bertherat J, Delemer B, Christin-Maitre S, Beckers A, Guilhem I, Rohmer V, Goichot B, Caron P, Baudin E, Chanson P, Groussin L, Du Boullay H, Weryha G, Lecomte P, Schillo F, Bihan H, Archambeaud F, Kerlan V, Bourcigaux N, Kuhn JM, Vergès B, Rodier M, Renard M, Sadoul JL, Binquet C, Goudet P. Unraveling the intrafamilial correlations and heritability of tumor types in MEN1: a Groupe d'étude des Tumeurs Endocrines study. Eur J Endocrinol. 2015 Dec;173(6):819-26. (P-D-C-CL-CO)
  4. Bousson V, Bergot C, Sutter B, Thomas T, Bendavid S, Benhamou CL, Blain H, Brazier M, Breuil V, Briot K, Chapurlat R, Chapuis L, Cohen Solal M, Fardellone P, Feron JM, Gauvain JB, Laroche M, Legrand E, Lespessailles E, Linglart A, Marcelli C, Roux C, Souberbielle JC, Tremollieres F, Weryha G, Cortet B; Groupe de Recherche et d’Information sur les Ostéoporoses (GRIO). Trabecular Bone Score: Where are we now? Joint Bone Spine. 2015 Oct;82(5):320-5. (P-D-C-CL-CO)
  5. Cuny T, Barlier A, Feelders R, Weryha G, Hofland LJ, Ferone D, Gatto F. Medical therapies in pituitary adenomas: Current rationale for the use and future perspectives. Ann Endocrinol (Paris). 2015 Feb;76(1):43-58. (P-D-C-CL-CO)
  6. Agopiantz M, Scheffler F, Faivre JC, Bonne S, Catoire P, Weryha G, Gompel A. [Evaluation of theoretical teaching of the French diploma of medical gynecology]. Gynecol Obstet Fertil. 2015 Jan;43(1):25-32. (P-D-C-CL-CO)
  7. Brunaud L, Boutami M, Nguyen-Thi PL, Finnerty B, Germain A, Weryha G, Fahey TJ 3rd, Mirallie E, Bresler L, Zarnegar R. Both preoperative alpha and calcium channel blockade impact intraoperative hemodynamic stability similarly in the management of pheochromocytoma. Surgery. 2014 Dec;156(6):1410-7; discussion1417-8. (P-D-C-CL-CO)
  8. Briot K, Cortet B, Roux C, Fardet L, Abitbol V, Bacchetta J, Buchon D, Debiais F, Guggenbuhl P, Laroche M, Legrand E, Lespessailles E, Marcelli C, Weryha G, Thomas T; Bone Section of the French Society for Rheumatology (SFR) and Osteoporosis Research and Information Group (GRIO). 2014 update of recommendations on the prevention and treatment of glucocorticoid-induced osteoporosis. Joint Bone Spine. 2014 Dec;81(6):493-501. (P-D-C-CL-CO)
  9. Gatto F, Grasso LF, Nazzari E, Cuny T, Anania P, Di Somma C, Colao A, Zona G, Weryha G, Pivonello R, Ferone D. Clinical outcome and evidence of high rate post-surgical anterior hypopituitarism in a cohort of TSH-secreting adenoma patients: Might somatostatin analogs have a role as first-line therapy? Pituitary. 2015 Oct;18(5):583-91. (P-D-C-CL-CO)
  10. Souberbielle JC, Benhamou CL, Cortet B, Rousière M, Roux C, Abitbol V, Annweiler C, Audran M, Bacchetta J, Bataille P, Beauchet O, Bardet R, Benachi A, Berenbaum F, Blain H, Borson-Chazot F, Breuil V, Briot K, Brunet P, Carel JC, Caron P, Chabre O, Chanson P, Chapurlat R, Cochat P, Coutant R, Christin-Maitre S, Cohen-Solal M, Combe C, Cormier C, Courbebaisse M, Debrus G, Delemer B, Deschenes G, Duquenne M, Fardellone P, Fouque D, Friedlander G, Gauvain JB, Groussin L, Guggenbuhl P, Houillier P, Hannedouche T, Jacot W, Javier RM, Jean G, Jeandel C, Joly D, Kamenicky P, Knebelmann B, Lafage-Proust MH, LeBouc Y, Legrand E, Levy-Weil F, Linglart A, Machet L, Maheu E, Mallet E, Marcelli C, Marès P, Mariat C, Maruani G, Maugars Y, Montagnon F, Moulin B, Orcel P, Partouche H, Personne V, Pierrot-Deseilligny C, Polak M, Pouteil-Noble C, Prié D, Raynaud-Simon A, Rolland Y, Sadoul JL, Salle B, Sault C, Schott AM, Sermet-Gaudelus I, Soubrier M, Tack I, Thervet É, Tostivint I, Touraine P, Tremollières F, Urena-Torres P, Viard JP, Wemeau JL, Weryha G, Winer N, Young J, Thomas T. Weakening osteopathies, chronic kidney disease, malabsorption, biological anomalies of calium/phosphorus metabolism: appropriate indications for a reasoned reimbursment of serum vitamin D measurement]. Ann Biol Clin (Paris). 2014 Jul-Aug;72(4):385-9. (P-D-C-CL-CO)
  11. Angelousi A, Girerd N, Benetos A, Frimat L, Gautier S, Weryha G, Boivin JM. Association between orthostatic hypotension and cardiovascular risk, cerebrovascular risk, cognitive decline and falls as well as overall mortality: a systematic review and meta-analysis. J Hypertens. 2014 Aug;32(8):1562-71; discussion 1571. (P-D-C-CL-CO)
  12. Collet A, Chatelin J, Agopiantz M, Valduga M, Bonnet C, Allou L, Lambert L, Gospodaru RN, Weryha G, Jonveaux P. [An adult patient with 49, XXXXY syndrome: further clinical and biological delineation]. Ann Biol Clin (Paris). 2014 May-Jun;72(3):371-7. (P-D-C-CL-CO)
  13. Castinetti F, Qi XP, Walz MK, Maia AL, Sansó G, Peczkowska M, Hasse-Lazar K, Links TP, Dvorakova S, Toledo RA, Mian C, Bugalho MJ, Wohllk N, Kollyukh O, Canu L, Loli P, Bergmann SR, Biarnes Costa J, Makay O, Patocs A, Pfeifer M, Shah NS, Cuny T, Brauckhoff M, Bausch B, von Dobschuetz E, Letizia C, Barczynski M, Alevizaki MK, Czetwertynska M, Ugurlu MU, Valk G, Plukker JT, Sartorato P, Siqueira DR, Barontini M, Szperl M, Jarzab B, Verbeek HH, Zelinka T, Vlcek P, Toledo SP, Coutinho FL, Mannelli M, Recasens M, Demarquet L, Petramala L, Yaremchuk S, Zabolotnyi D, Schiavi F, Opocher G, Racz K, Januszewicz A, Weryha G, Henry JF, Brue T, Conte-Devolx B, Eng C, Neumann HP. Outcomes of adrenal-sparing surgery or total adrenalectomy in phaeochromocytoma associated with multiple endocrine neoplasia type 2: an international retrospective population-based study. Lancet Oncol. 2014 May;15(6):648-55. (P-D-C-CL-CO)
  14. Blain H, Rolland Y, Beauchet O, Annweiler C, Benhamou CL, Benetos A, Berrut G, Audran M, Bendavid S, Bousson V, Briot K, Brazier M, Breuil V, Chapuis L, Chapurlat R, Cohen-Solal M, Cortet B, Dargent P, Fardellone P, Feron JM, Gauvain JB, Guggenbuhl P, Hanon O, Laroche M, Kolta S, Lespessailles E, Letombe B, Mallet E, Marcelli C, Orcel P, Puisieux F, Seret P, Souberbielle JC, Sutter B, Trémollières F, Weryha G, Roux C, Thomas T; Groupe de recherche et d’information sur les ostéoporoses et la Société française de gérontologie et gériatrie. Usefulness of bone density measurement in fallers. Joint Bone Spine. 2014 Oct;81(5):403-8. (P-D-C-CL-CO)
  15. Delemer B, Chanson P, Foubert L, Borson-Chazot F, Chabre O, Tabarin A, Weryha G, Cortet-Rudelli C, Raingeard I, Reznik Y, Reines C, Bisot-Locard S, Castinetti F.Patients lost to follow-up in acromegaly: results of the ACROSPECT study. Eur J Endocrinol. 2014 Apr 19;170(5):791-7. (P-D-C-CL-CO)
  16. Agopiantz M, Corbonnois P, Sorlin A, Bonnet C, Klein M, Hubert N, Pascal-Vigneron V, Jonveaux P, Cuny T, Leheup B, Weryha G. Endocrine disorders in Woodhouse-Sakati syndrome: a systematic review of the literature. J Endocrinol Invest. 2014 Jan;37(1):1-7. (P-D-C-CL-CO)
  17. Souberbielle JC, Benhamou CL, Cortet B, Rousière M, Roux C, Abitbol V, Audran M, Bachetta J, Beauchet O, Blain H, Breuil V, Briot K, Brunet P, Chanson P, Cormier C, Courbebaisse M, Fardellone P, Fouque D, Friedlander G, Gauvain JB, Groussin L, Houillier P, Jacot W, Jean G, Kamenicky P, Lafage-Proust MH, Legrand E, Levy-Weil F, Linglart A, Mallet E, Marcelli C, Maruani G, Montagnon F, Personne V, Prié D, Raynaud-Simon A, Rolland Y, Salle B, Sault C, Schott AM, Thervet E, Urena-Torres P, Viard JP, Weryha G, Pierrot-Deseilligny C, Young J, Thomas T. [HAS report on vitamin D measurement: don't go from an extreme situation to another as extreme situation]. Presse Med. 2014 Jan;43(1):5-8. (P-D-C-CL-CO)
  18. Weryha G, Angelousi A, Diehdiou D, Cuny T. [Bone and androgens]. Presse Med. 2014 Feb;43(2):180-5. (P-D-C-CL-CO)
  19. Bausch B, Wellner U, Bausch D, Schiavi F, Barontini M, Sanso G, Walz MK, Peczkowska M, Weryha G, Dall'igna P, Cecchetto G, Bisogno G, Moeller LC, Bockenhauer D, Patocs A, Rácz K, Zabolotnyi D, Yaremchuk S, Dzivite-Krisane I, Castinetti F, Taieb D, Malinoc A, von Dobschuetz E, Roessler J, Schmid KW, Opocher G, Eng C, Neumann HP. Long-term prognosis of patients with pediatric pheochromocytoma. Endocr Relat Cancer. 2013 Dec 16;21(1):17-25. (P-D-C-CL-CO)
  20. Benetos A, Novella JL, Guerci B, Blickle JF, Boivin JM, Cuny P, Delemer B, Gabreau T, Jan P, Louis J, Passadori Y, Petit JM, Weryha G. Pragmatic diabetes management in nursing homes: individual care plan. J Am Med Dir Assoc. 2013 Nov;14(11):791-800. (P-D-C-CL-CO)
  21. Koufany M, Chappard D, Netter P, Bastien C, Weryha G, Jouzeau JY, Moulin D. The peroxisome proliferator-activated receptor y agonist pioglitazone preserves bone microarchitecture in experimental arthritis by reducing the interleukin-17-dependent osteoclastogenic pathway. Arthritis Rheum. 2013 Dec;65(12):3084-95. (P-D-C-CL-CO)
  22. Le Chatton M, Zaccabri A, Agopiantz M, Leheup B, Weryha G, Foliguet B. [Azoospermia and 45,X/46,XY chromosomal mosaicism: a case report]. Gynecol Obstet Fertil. 2013 Mar;41(3):203-6. (P-D-C-CL-CO)
  23. Thevenon J, Bourredjem A, Faivre L, Cardot-Bauters C, Calender A, Murat A, Giraud S, Niccoli P, Odou MF, Borson-Chazot F, Barlier A, Lombard-Bohas C, Clauser E, Tabarin A, Parfait B, Chabre O, Castermans E, Beckers A, Ruszniewski P, Le Bras M, Delemer B, Bouchard P, Guilhem I, Rohmer V, Goichot B, Caron P, Baudin E, Chanson P, Groussin L, Du Boullay H, Weryha G, Lecomte P, Penfornis A, Bihan H, Archambeaud F, Kerlan V, Duron F, Kuhn JM, Verges B, Rodier M, Renard M, Sadoul JL, Binquet C, Goudet P. Higher risk of death among MEN1 patients with mutations in the JunD interacting domain: a Groupe d'etude des Tumeurs Endocrines (GTE) cohort study. Hum Mol Genet. 2013 May 15;22(10):1940-8. (P-D-C-CL-CO)
  24. Janin C, Pascal Vigneron V, Weryha G, Leheup B. Clinical audit concerning the quality of management in patients with classic form of congenital adrenal hyperplasia. Ann Endocrinol (Paris). 2013 Feb;74(1):13-26. (P-D-C-CL-CO)
  25. Cuny T, Pertuit M, Sahnoun-Fathallah M, Daly A, Occhi G, Odou MF, Tabarin A, Nunes ML, Delemer B, Rohmer V, Desailloud R, Kerlan V, Chabre O, Sadoul JL, Cogne M, Caron P, Cortet-Rudelli C, Lienhardt A, Raingeard I, Guedj AM, Brue T, Beckers A, Weryha G, Enjalbert A, Barlier A. Genetic analysis in young patients with sporadic pituitary macroadenomas: besides AIP don't forget MEN1 genetic analysis. Eur J Endocrinol. 2013 Mar 15;168(4):533-41. (P-D-C-CL-CO)
  26. Rizzoli R, Boonen S, Brandi ML, Bruyère O, Cooper C, Kanis JA, Kaufman JM, Ringe JD, Weryha G, Reginster JY. Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Curr Med Res Opin. 2013 Apr;29(4):305-13. (P-D-C-CL-CO)
  27. Kaufman JM, Reginster JY, Boonen S, Brandi ML, Cooper C, Dere W, Devogelaer JP, Diez-Perez A, Kanis JA, McCloskey E, Mitlak B, Orwoll E, Ringe JD, Weryha G, Rizzoli R. Treatment of osteoporosis in men. Bone. 2013 Mar;53(1):134-44. (P-D-C-CL-CO)
  28. Rizzoli R, Adachi JD, Cooper C, Dere W, Devogelaer JP, Diez-Perez A, Kanis JA, Laslop A, Mitlak B, Papapoulos S, Ralston S, Reiter S, Werhya G, Reginster JY. Management of glucocorticoid-induced osteoporosis. Calcif Tissue Int. 2012 Oct;91(4):225-43. (P-D-C-CL-CO)
  29. Renard E, Langbour-Remy C, Klein M, Le Bouc Y, Weryha G, Cuny T. Severe hypoglycemia with "Big"-IGF-2 oversecretion by a giant phyllode tumor of the breast: a rare case of non-islet cell tumor-induced hypoglycemia (NICTH). Ann Endocrinol (Paris). 2012 Nov;73(5):488-91. (P-D-C-CL-CO)
  30. Saveanu A, Muresan M, De Micco C, Taieb D, Germanetti AL, Sebag F, Henry JF, Brunaud L, Enjalbert A, Weryha G, Barlier A. Expression of somatostatin receptors, dopamine Dâ‚‚ receptors, noradrenaline transporters, and vesicular monoamine transporters in 52 pheochromocytomas and paragangliomas. Endocr Relat Cancer. 2011 Mar 21;18(2):287-300. (P-D-C-CL-CO)
  31. Regnault V, Perret-Guillaume C, Kearney-Schwartz A, Max JP, Labat C, Louis H, Wahl D, Pannier B, Lecompte T, Weryha G, Challande P, Safar ME, Benetos A, Lacolley P. Tissue factor pathway inhibitor: a new link among arterial stiffness, pulse pressure, and coagulation in postmenopausal women. Arterioscler Thromb Vasc Biol. 2011 May;31(5):1226-32. (P-D-C-CL-CO)

 

ZIAD ALIZADEH Behrooz

  1. Vaez A, van der Most PJ, Prins BP, Snieder H, van den Heuvel E, Alizadeh BZ, Nolte IM. lodGWAS: a software package for genome-wide association anal-ysis of biomarkers with a limit of detection. Bioinformatics. 2016 Jan 22. pii: btw021. [Epub ahead of print]. (P-D-C-CL-CO)
  2. Rump P, Jazayeri O, van Dijk-Bos KK, Johansson LF, van Essen AJ, Verheij JB, Veenstra-Knol HE, Redeker EJ, Mannens MM, Swertz MA, Alizadeh BZ, van Ravenswaaij-Arts CM, Sinke RJ, Sikkema-Raddatz B. Whole-exome sequencing is a powerful approach for establishing the etiological diagnosis in patients with intellectual disability and microcephaly. BMC Med Genomics. 2016 Feb 4;9(1):7. (P-D-C-CL-CO)
  3. Prins BP, ……<50 coauthors> ..Alizadeh BZ. Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.  PLOS Medicine- 2016 21;13(6):e1001976. doi: 10.1371/journal.pmed.1001976. (P-D-C-CL-CO)
  4. Ligthart S, Vaez A, Hsu Y, Inflammation Working Group of the CHARGE Consortium, PMI-WG--XCP, LifeLines Cohort Study, Alizadeh BZ, Stolk R, Uitterlinden AG, Hofman A, Franco O, Dehghan A. Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation. BMC Genomics- 2016 10;17:443. (P-D-C-CL-CO)
  5. Okbay A, Baselmans BM, … Alizadeh BZ , …, Bartels M, Cesarini D. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet. 2016 Jul 27;48(8):970. doi: 10.1038/ng0816-970c. (P-D-C-CL-CO)
  6. Okbay A, … Alizadeh BZ , …, Beauchamp JP,Cesarini D, Benjamin DJ. Genome-wide association study identifies 74 loci associated with educational attainment. Nature. 2016 May 11;533(7604):539-42. doi: 10.1038/nature17671. (P-D-C-CL-CO)
  7. Day FR, Ruth KS, …………… ALIZADEH BZ , ……., Perry JRB, Murray A. Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA double strand break repair. Nat Genet. 2015 Nov;47(11):1294-303. (P-D-C-CL-CO)
  8. Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T, Abedian S, Cheon JH, Cho J, Daryani NE, Franke L, Fuyuno Y, Hart A, Juyal RC, Juyal G, Kim WH, Morris AP, Poustchi H, Newman WG, Midha V, Orchard TR, Vahedi H, Sood A, Sung JJ, Malekzadeh R, Westra HJ, Yamazaki K, Yang SK; International Multiple Sclerosis Genetics Consortium; International IBD Genetics Consortium, Barrett JC, Franke A, Alizadeh BZ, Parkes M, B K T, Daly MJ, Kubo M, Anderson CA, Weersma RK. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nat Genet. 2015 Sep;47(9):979-86. (P-D-C-CL-CO)
  9. Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, de Geus EJ, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S; Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium (Corporate Collaborator), Martin NG, Medland SE, Metspalu A, Milani L, Noethen MM, Potash JB, Rietschel M, Rietveld CA, Ripke S, Shi J; Social Science Genetic Association Consortium Corporate Collaborator, Willemsen G, Zhu Z, Boomsma DI, Wray NR, Penninx BW; (ALIZADEH BZ. in collaborators list - 294). Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium Corporate Collaborator; Social Science Genetic Association Consortium Corporate Collaborator. The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects. Mol Psychiatry. 2015 Jun;20(6):735-43. (P-D-C-CL-CO)
  10. Vaez A, Jansen R, Prins BP, Hottenga JJ, de Geus EJ, Boomsma DI, Penninx BW, Nolte IM, Snieder H, Alizadeh BZ. In Silico Post Genome-Wide Association Studies Analysis of C-Reactive Protein Loci Suggests an Important Role for Interferons. Circ Cardiovasc Genet. 2015 Jun;8(3):487-97. (P-D-C-CL-CO)
  11. Locke AE, Kahali B, ……, Hirschhorn JN, Loos RJ, Speliotes EK. (ALIZADEH BZ. in collaborators list - 2101). Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;12;518:197-206. (P-D-C-CL-CO)
  12. Shungin D, Winkler TW,..,Cupples LA, Morris AP, Lindgren CM, Mohlke KL. New genetic loci link adipose and insulin biology to body fat distribution. (ALIZADEH BZ. in collaborators list - 2200 collaborators). Nature. 2015 12;518:187-96. (P-D-C-CL-CO)
  13. Abbasi A, Deetman PE, Corpeleijn E, Gansevoort RT, Gans RO, Hillege HL, van der Harst P, Stolk RP, Navis G, Alizadeh BZ, Bakker SJ. Bilirubin as a potential causal factor in type 2 diabetes risk: a Mendelian randomization study. Diabetes. 2015 Apr;64(4):1459-69. (P-D-C-CL-CO)
  14. Dijkstra AE, Boezen HM, van den Berge M, Vonk JM, Hiemstra PS, Barr RG, Burkart KM, Manichaikul A, Pottinger TD, Silverman EK, Cho MH, Crapo JD, Beaty TH, Bakke P, Gulsvik A, Lomas DA, Bossé Y, Nickle DC, Paré PD, de Koning HJ, Lammers JW, Zanen P, Smolonska J, Wijmenga C, Brandsma CA, Groen HJ, Postma DS; LifeLines Cohort Study group. (ALIZADEH BZ. in collaborators list - 17) Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD. Eur Respir J. 2015 Jan;45(1):60-75. (P-D-C-CL-CO)
  15. Perry JR, Day F, Elks CE, …. Alizadeh BZ, ……Widen E, Zygmunt M, Murray A, Easton DF,

Stefansson K, Murabito JM, Ong KK. (266 collaborators). Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 2014, 2;514:92-7. (P-D-C-CL-CO)

  1. Quee PJ, Meijer JH, Islam MA, Aleman A, Alizadeh BZ, Meijer CJ, van den Heuvel ER; GROUP Investigators.  Premorbid adjustment profiles in psychosis and the role of familial factors. J Abnorm Psychol. 2014;123:578-87. (P-D-C-CL-CO)
  2. Kraja AT, Chasman DI….. Vaidya D, O'Donnell CJ, Benjamin EJ, Alizadeh BZ, Prokopenko I, Meigs JB, Borecki IB. Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. 2014;112:317-38. (P-D-C-CL-CO)
  3. Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV,…; LifeLines Cohort Study, …., van Duijn CM, Witteman JC, Chakravarti A, Rao DC.  (ALIZADEH BZ. in collaborators list - 17). Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. Am J Hum Genet. 2014 3;95:24-38. (P-D-C-CL-CO)
  4. Eny KM, Lutgers HL, Maynard J, Klein BE, Lee KE, Atzmon G, Monnier VM, van Vliet-

Ostaptchouk JV, Graaff R, van der Harst P, ….,Lyons TJ, Howard K, Klein R, Crandall JP, Barzilai N, Milman S, Ben-Avraham D; LifeLines Cohort Study Group; DCCT/EDIC Research Group, Wolffenbuttel BH, Paterson AD.  (ALIZADEH BZ. in collaborators list - 17). GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence. Diabetologia. 2014;57:1623-34. (P-D-C-CL-CO)

  1. Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, ….., Vonk JM, Nawijn MC, Groen HJ, Timens W, Boezen HM, Postma DS. (ALIZADEH BZ. in collaborators list - 17). Susceptibility to chronic mucus hypersecretion, a genome wide association study. LifeLines Cohort study. PLoS One. 2014 8;9:e91621. (P-D-C-CL-CO)
  2. van der Most PJ, Vaez A, Prins BP, Munoz ML, Snieder H, Alizadeh BZ, Nolte IM.

QCGWAS: A flexible R package for automated quality control of genome-wide association results. Bioinformatics. 2014 Jan 13. (P-D-C-CL-CO)

  1. Evans DM, Brion MJ, Paternoster L, Kemp JP, McMahon G, Munafò M, Whitfield JB, Medland SE, Montgomery GW; GIANT Consortium; CRP Consortium; TAG Consortium, Timpson NJ, St Pourcain B, Lawlor DA, Martin NG, Dehghan A, Hirschhorn J, Davey Smith G. (ALIZADEH BZ. in collaborators list - 605). Mining the human phenome using allelic scores that index biological intermediates.. PLoS Genet. 2013;9:e1003919. (P-D-C-CL-CO)
  2. de Jong K, Boezen HM, Kromhout H, Vermeulen R, Postma DS, Vonk JM. (ALIZADEH BZ. in collaborators list - 17). Pesticides and other occupational exposures are associated with airway obstruction: the LifeLines cohort study. LifeLines Cohort study. Occup Environ Med. 2014 ;71:88-96. (P-D-C-CL-CO)
  3. Sadjadi A, Derakhshan MH, Yazdanbod A, Boreiri M, Parsaeian M, Babaei M, Alimohammadian M, Samadi F, Etemadi A, Pourfarzi F, Ahmadi E, Delavari A, Islami F, Farzadfar F, Sotoudeh M, Nikmanesh A, Alizadeh BZ, de Bock GH, Malekzadeh R. Neglected role of hookah and opium in gastric carcinogenesis: a cohort study on risk factors and attributable fractions. Int J Cancer. 2014 1;134:181-8. (P-D-C-CL-CO)
  4. Quee PJ, Alizadeh BZ, Aleman A, van den Heuvel ER; GROUP Investigators. Cognitive subtypes in non-affected siblings of schizophrenia patients: characteristics and profile congruency with affected family members. Psychol Med. 2014;44:395-405. (P-D-C-CL-CO)
  5. Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, …..,  van Duijn CM, Visscher PM, Benjamin DJ, Cesarini D, Koellinger PD. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science. 2013,21;340:1467-71. (P-D-C-CL-CO)
  6. Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, …..  Felix JF, Alizadeh BZ, Cupples LA, Perry JR, Morris AP. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet. 2012 5;91:744-53. (P-D-C-CL-CO)
  7. Sadjadi A, Yazdanbod A, Lee YY, Boreiri M, Samadi F, Alizadeh BZ, Islami F, Fyfe V, Babaei M, Namazi MJ, Going JJ, Sotoudeh M, de Bock GH, Malekzadeh R, Derakhshan MH. Serum ghrelin; a new surrogate marker of gastric mucosal alterations in upper gastrointestinal carcinogenesis. PLoS One. 2013 30;8:e74440. (P-D-C-CL-CO)
  8. Stolk L, …. Alizadeh BZ … Visser JA, Lunetta KL. Meta-analysis of genome-wide association studies of age at menopause: novel loci highlight DNA repair and immune pathways. Nat. Genet. 2012 22;44:260-8. (P-D-C-CL-CO)
  9. Vehof J, Burger H, Wilffert B, Al Hadithy A, Alizadeh BZ, Snieder H; Clinical response to antipsychotic drug treatment: Association study of polymorphisms in six candidate genes. GROUP investigators. Eur Neuropsychopharmacol. 2012 Feb 29. (P-D-C-CL-CO)
  10. Sas AA, Jamshidi Y, Zheng D, Wu T, Alizadeh BZ, Korf J, Spector TD, Snieder H. The age-dependancy of genetic and environmental influences on serum cytokine levels; a twin study. Cytokine, 2012 60:108-13. (P-D-C-CL-CO)
  11. Kaas A, Pfleger C, Kharagjitsingh AV, Schloot NC, Hansen L, Buschard K, Koeleman BP, Roep BO, Mortensen HB, Alizadeh BZ; on behalf of the Havidoere Study Group on Childhood Diabetes. (ALIZADEH BZ. in collaborators list - 34).Association between age, IL-10, IFNγ, stimulated C-peptide and disease progression 1 diabetes. in children with newly diagnosed Type. Diabet Med. 2012 29:734-741. (P-D-C-CL-CO)
  12. Miedema KG, Tissing WJ, Te Poele EM, Kamps WA, Alizadeh BZ, Kerkhof M, de Jongste JC, Smit HA, de Pagter AP, Bierings M, Boezen HM, Postma DS, de Bont ES, Koppelman GH. Polymorphisms in the TLR6 gene associated with the inverse association between childhood acute lymphoblastic leukemia and atopic disease. Leukemia. 2012 Jun;26(6):1203-10. (P-D-C-CL-CO)
  13. Kharagjitsingh A, de Ridder M, Alizadeh B, Veeze H, Bruining G, Roep B, Koeleman BP. Genetic correlates of early accelerated infant growth associated with juvenile-onset type 1 diabetes. Pediatr Diabetes. 2012 13:266-271. (P-D-C-CL-CO)
  14. Wain L1, Verwoert GC, ………. Alizadeh BZ30, ……………, Tobin MD, Elliott P, van Duijn CM. (ALIZADEH BZ. in collaborators list - 653).Genome-wide association study of Pulse Pressure and Mean Arterial Pressure identifies seven novel loci. International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS). Nat. Genet. 2011 11;43:1005-11. (P-D-C-CL-CO)
  15. Chambers JC, Zhang W, Sehmi J. Li X, ….. Alizadeh BZ…… Kathryn L, Järvelin MR, Elliot P, and Kooner JS. (ALIZADEH BZ. in collaborators list - 1342). Genome-wide association study identifies loci influencing plasma levels of liver enzymes. Nat. Genet. 2011, 16;43:1131-8. (P-D-C-CL-CO)
  16. Dehghan A, Dupuis J …., Alizadeh BZ …., Koenig W, Ballantyne C, Witteman JCM, Benjamin EJ, Perola MP, Chasman DI. Meta-analysis of genome-wide association studies in 81,059 subjects identifies 12 novel loci for C-reactive protein serum levels. Circulation. 2011, 22;123:731-8. (P-D-C-CL-CO)
  17. Gorlova O, Martin JE, Rueda B, Koeleman BPC., …., Alizadeh BZ9, …. Mayes MD, Martin J38. (ALIZADEH BZ. in collaborators list - 25). Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy. PloS Genetic, 2011 7:e1002178. (P-D-C-CL-CO)
  18. Miedema KGE, Poele EMt, Tissing W, Postma DS, Koppelman GH, de Pagter AD, Alizadeh BZ, Boezen MH, de Bont ESJM.Association of polymorphisms in the TLR4 gene with the risk of developing neutropenia in children with leukemia. Leukemia. 2011, 25:995-1000. (P-D-C-CL-CO)
  19. Miedema KGE, Tissing WJE, Poele EMT, Postma DS, Koppelman GH, Boezen MH, Alizadeh BZ, Kamps WA, de Bont ESJM. Genetic variation in TLRs and CD14 genes as explanation between reverse association between childhood ALL and atopic disease. Leukemia 2011;164:890-2. (P-D-C-CL-CO)
  20. Swart M, Bruggeman R, Larøi F, Alizadeh BZ, Kema I, Kortekaas R, Wiersma D, Aleman A.3# COMT Val158Met polymorphism, verbalizing of emotion and activation of affective brain systems. Neuroimage. 2011;55:338-44. (P-D-C-CL-CO)
  21. Pot LM, Alizadeh BZ, Ahrenberg D, Coenraads P-J, Snieder H, Blömeke B.  Comment on "No major role for glutathione S-transferase gene polymorphisms in sensitization to para-phenylenediamine and other xenobiotics: a study of association and a meta-analysis: Reply from authors.. BrJ Dermatol. 2011,164:890-2. (P-D-C-CL-CO)
  22. Diaz-Gallo LM, Espino-Paisán L, Fransen K, van Sommeren S, Gómez-García M,  Cardeña C, Rodrigo L, …..,  Ponsioen CY,  Wijmenga C, Roberts RL, Weersma RK, Merriman TR, Alizadeh BZ*, Martin J*. The PTPN22 Gene Influences Genetic Predisposition to Ulcerative Colitis and Crohn’s Disease. Inflamm Bowel Dis. 2011, 17:2287-94. (P-D-C-CL-CO)
  23. Roberts RL, Hollis-Moffatt JE,  Gómez-García M, Fransen K, Ponsioen CY, Crusius JBA, Wijmenga C, Martín J, Weersma RK, Merriman TR, Barclay ML, Gearry RB, Alizadeh BZ. Preliminary evidence of association of Protein-tyrosine Phosphatase Nonreceptor type substrate 1 (PTPNS1) with inflammatory bowel disease. Inflamm Bowel Dis. 2011;17:19-21. (P-D-C-CL-CO)
  24. Koning JP, Vehof J, Burger H, Wilffert B, Al Hadithy A, Alizadeh BZ, van Harten PN, Snieder H;  Genetic Risk and Outcome in Psychosis (GROUP) investigators. Association of two DRD2 gene polymorphisms with acute and tardive antipsychotic-induced movement disorders in young Caucasian patients. Psychopharmacology. 2011,219:727-36. (P-D-C-CL-CO)
  25. Martín JE, Alizadeh BZ, ………Koeleman BPC, Martín J. Evidence for the PTPN22 R620W polymorphism being the sole common risk variant for rheumatoid arthritis in the 1p13.2 region. J Reumatol. 2011, 38;11:2290-6. (P-D-C-CL-CO)
  26. Lichtenbelt KD, Alizadeh BZ, Scheffer PG, Stoutenbeek P, Schielen P, Page-Christiaens GCM, Schuring-Blom GH. Trend analysis of invasive prenatal diagnosis in the Netherlands 2000 to 2010. Prenatal Diagnosis, 2011, 31:765-7. (P-D-C-CL-CO)
  27. Euser AM, Finken MJ, Kharagjitsingh AV, Alizadeh BZ, Roep BO, Meulenbelt I, Dekker FW, Wit JM. IGF1 promoter polymorphism and cranial growth in individuals born very preterm. Horm Res Paediatr. 2011;76:27-34. (P-D-C-CL-CO)
  28. Hassan MO, Jaju D, Voruganti VS, Bayoumi RA, Albarwani S, Al-Yahyaee S, Aslani A, Snieder H, Lopez-Alvarenga JC, Al-Anqoudi ZM, Alizadeh BZ, Comuzzie AG. Genome-wide Linkage Analysis of Blood Pressure and Hemodynamic Parameters Under Mental and Physical Stress in Extended Omani Arab Pedigrees; The Oman Family Study. Twin Res Hum Genet. 2011 14:257-67. (P-D-C-CL-CO)

 

El SHAMIEH Said

  1. BOULANGER-SCEMAMA E, EL SHAMIEH S, DÉMONTANT V, CONDROYER C, ANTONIO A, MICHIELS E, BOYARD F, SARAIVA JP, LETEXIER M, SOUIED E, MOHAND-SAÏD S, SAHEL JA, ZEITZ C AND AUDO I.  Next-Generation Sequencing applied to a large French cone and cone-rod dystrophy cohort: mutation spectrum and new genotype-phenotype correlation. Orphanet Journal of Rare Diseases. 2015 Jun 24;10:85. (P-D-C-CL-CO)
  2. KIKUCHI S, KAMEYA S, GOCHO K, EL SHAMIEH S, AKEO K, SUGAWARA Y, YAMAKI K, ZEITZ C, AUDO I, TAKAHASHI H. Cone dystrophy in patient with homozygous RP1L1 mutation. BioMed Research International. 2015:545243. (P-D-C-CL-CO)
  3. EL SHAMIEH S, BOULANGER-SCEMAMA E, LANCELOT ME, ANTONIO A, DÉMONTANT V, CONDROYER C, LETEXIER M, SARAIVA JP, SAHEL JA, AUDO I, ZEITZ C. Targeted next generation sequencing identifies novel mutations in RP1 as a relatively common cause of autosomal recessive rod-cone dystrophy. BioMed Research International. 2015 : 485624. (P-D-C-CL-CO)
  4. EL SHAMIEH S, NEUILLÉ M, TERRAY A, ORHAN E, CONDROYER C, DÉMONTANT V, MICHIELS C, ANTONIO A, BOYARD F, LANCELOT ME, LETEXIER M, SARAIVA JP, LÉVEILLARD T, MOHAND-SAÏD S, GOUREAU O, SAHEL JA, ZEITZ C, AUDO I. Whole exome sequencing identifies KIZ as a ciliary gene underlying autosomal recessive rod-cone dystrophy. The American Journal of Human Genetics. 2014. Apr 3;94(4):625-33. (P-D-C-CL-CO)
  5. NEUILLÉ M, EL SHAMIEH S, ORHAN E, MICHIELS C, ANTONIO A, LANCELOT ME, CONDROYER C, BUJAKOWSKA K, POCH O, SAHEL JA, AUDO I, ZEITZ C. Lrit3nob6 a novel mouse model of complete congenital stationary night blindness. PLoS ONE.  2014 Mar 5;9(3):e90342. (P-D-C-CL-CO)